A true tumor microenvironment is composed of many different cell types within an organ, including tumor cells, stromal cells, immune cells, pericytes, endothelial cells, and the extracellular matrix (ECM). Culturing these cells in 3D allows them to acquire tissue-like characteristics. Although only tens of micrometers in size, these 3D structures retain the complexity of tissues, creating an environment that closely mimics the in vivo situation.
CellBall Biomedical establishes 3D cell-based drug screening models using next-generation tumor cell lines within an ECM-mimicking environment. This provides researchers with conditions that closely resemble the true tumor microenvironment, yielding more accurate and reliable drug screening results, saving valuable time, and accelerating the progress of experimental development.
